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Prevention of Xerostomia-Related Dental Caries in Irradiated Cancer Patients

Samuel Dreizen

The University of Texas Dental Science Institute and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

Lee R. Brown

The University of Texas Dental Science Institute and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

Thomas E. Daly

The University of Texas Dental Science Institute and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

Joe B. Drane

The University of Texas Dental Science Institute and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

Three caries preventative regimens: oral hygiene ; oral hygiene and topical fluoride; and oral hygiene, topical fluoride, and sucrose restriction were evaluated in patients with cancer given xerostomia-producing radiotherapy. The oral hygiene-fluoride gel combination was remarkably effective in protecting these high risk patients from caries, regardless of the cariogenicity of the diet.

Journal of Dental Research, Vol. 56, No. 2, 99-104 (1977)
DOI: 10.1177/00220345770560022101


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