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Journal of Dental Research
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Proteolipid and Calculus Matrix Calcification In Vitro

J. Ennever

Dental Science Institute, The University of Texas Dental Branch, Houston, Texas 77030, USA

J.J. Vogel

Dental Science Institute, The University of Texas Dental Branch, Houston, Texas 77030, USA

L.J. Riggan

Dental Science Institute, The University of Texas Dental Branch, Houston, Texas 77030, USA

S.B. Paoloski

Dental Science Institute, The University of Texas Dental Branch, Houston, Texas 77030, USA

The initiator of calculus matrix calcification, in vitro, was isolated. Crude phospholipid, known to contain the factor, was separated into five fractions by column chromatography. A single protein-containing fraction induced apatite formation during incubation in a metastable calcium phosphate solution. The nucleating fraction was identified as a proteolipid.

Journal of Dental Research, Vol. 56, No. 2, 140-142 (1977)
DOI: 10.1177/00220345770560020701
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