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What's this?

Phagocytosis of Collagen by Human Gingival Fibroblasts in Vitro

Toshihiko Yajima

Department of Internal Medicine, The University of Texas Health Science Center, Dental Branch, Houston, Texas 77030, USA

George G. Rose

Department of Internal Medicine, The University of Texas Health Science Center, Dental Branch, Houston, Texas 77030, USA

Human gingival fibroblasts cultivated on collagen-coated cover slips had collagen fibrils in deep folds of the cell membranes after one hour and fully interiorized fibrils by 24 hours. In 5-day sections, fibrils were within dense bodies, some containing multiple dense granules (40 to 50 nm) aligned along the surface of the interiorized collagen fibrils.

Journal of Dental Research, Vol. 56, No. 10, 1271-1277 (1977)
DOI: 10.1177/00220345770560103201
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