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Clinical and Materials Sciences The Effect of Skylab on the Chemical Composition of Saliva

The University of Texas Dental Branch, Dental Science Institute, P. O. Box 20068, Houston, Texas 77025, The Lyndon B. Johnson Space Center, and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

William J. Frome

The University of Texas Dental Branch, Dental Science Institute, P. O. Box 20068, Houston, Texas 77025, The Lyndon B. Johnson Space Center, and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

Merrill G. Wheatcroft

The University of Texas Dental Branch, Dental Science Institute, P. O. Box 20068, Houston, Texas 77025, The Lyndon B. Johnson Space Center, and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

Linda J. Riggan

The University of Texas Dental Branch, Dental Science Institute, P. O. Box 20068, Houston, Texas 77025, The Lyndon B. Johnson Space Center, and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

Norman E. Bussell

The University of Texas Dental Branch, Dental Science Institute, P. O. Box 20068, Houston, Texas 77025, The Lyndon B. Johnson Space Center, and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

Dennis A. Johnston

The University of Texas Dental Branch, Dental Science Institute, P. O. Box 20068, Houston, Texas 77025, The Lyndon B. Johnson Space Center, and The University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas 77030, USA

The levels of specific proteins and electrolytes in stimulated whole saliva were monitored in Skylab crew members before and after each mission. With few exceptions, mission-associated compositional changes in saliva were relatively minimal. There were no changes in Ca++, K⁺, PO₄, Cl^-, albumin, or IgG concentrntions. There were slight decreases in total protein coinciding with moderate saliva flow rate increases iminediately before and after each flight. Other changes included diminutions in Na⁺ and lysozyme, and elevations in Mg⁺⁺ and IgA. The IgA increase was the most pronounced mission-associated change observed.

Journal of Dental Research, Vol. 56, No. 10, 1137-1143 (1977)
DOI: 10.1177/00220345770560100101


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