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Journal of Dental Research
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Extracellular Dextran Hydrolase from Streptococcus mutans Strain 6715

David W. Ellis

Laboratory of Oral Microbiology, Indiana University School of Dentistry, Indianapolis, Indiana 46202, USA

Chris H. Miller

Laboratory of Oral Microbiology, Indiana University School of Dentistry, Indianapolis, Indiana 46202, USA

Streptococcus mutans strain 6715 was shown to produce an extracellular dextranase with endohydrolytic {alpha}-(1->6)-glucan-6-glucanohydrolase activity. The enzyme degraded soluble polymers produced by some oral streptococci but did not disperse the streptococcal plaques tested. Enzyme levels in the culture supernatant were elevated in sucrose and sucrose plus glucose cultures but remained at basal levels in glucose and dextran plus glucose cultures.

Journal of Dental Research, Vol. 56, No. 1, 57-69 (1977)
DOI: 10.1177/00220345770560011301
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Home page
 Microbiol. Mol. Biol. Rev.Home page
E. Khalikova, P. Susi, and T. Korpela
Microbial Dextran-Hydrolyzing Enzymes: Fundamentals and Applications
Microbiol. Mol. Biol. Rev., June 1, 2005; 69(2): 306 - 325.
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