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Journal of Dental Research
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Xylitol Binding in Human Dental Plaque

Kauko K. Mäkinen

Institute of Dentistry, University of Turku, SF-20520 Turku, 52, Finland

Maarit Rekola

Institute of Dentistry, University of Turku, SF-20520 Turku, 52, Finland

Human dental plaque and whole saliva sediment were tested for their ability to bind 14C-labeled sucrose, fructose, glucose, sorbitol, and xylitol. Sucrose, glucose, sorbitol, and fructose were bound to all materials tested, in this decreasing order. The binding was strongest with plaque given a five-second ultrasonic shock, and lowest with salivary sediment. Xylitol was only insignificantly bound, indicating that plaque microorganisms possess specific recognition sites for xylitol to a very restricted extent.

Journal of Dental Research, Vol. 55, No. 5, 900-904 (1976)
DOI: 10.1177/00220345760550053101
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K. K. Makinen and K. K. Virtanen
Effect of 4.5-Year Use of Xylitol and Sorbitol on Plaque
Journal of Dental Research, March 1, 1978; 57(3): 441 - 446.
[Abstract] [PDF]