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Journal of Dental Research
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Latex Spheres as Immunologic Markers to Demonstrate the Binding of Human Salivary Immunoglobulins to Streptococcus mutans

G.R. Riviere

Naval Dental Research Institute, Great Lakes, Illinois 60088, USA

W.R. Cotton

Naval Dental Research Institute, Great Lakes, Illinois 60088, USA

J.L. Derkowski

Naval Dental Research Institute, Great Lakes, Illinois 60088, USA

A scanning electron microscopy technique is described that uses latex beads as immunologic markers for detecting the interaction of salivary antibody with Streptococcus mutans. A Labeling Index (beads per bacterial cell) demonstrated that human salivary antibodies bound at a significantly greater degree to S mutans than to non oral bacteria.

Journal of Dental Research, Vol. 55, No. 5, 879-885 (1976)
DOI: 10.1177/00220345760550052801


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