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Journal of Dental Research
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Effects of Anti-Inflammatory Steroids on Mouse Embryonic Movements During Palatal Development

Bruce E. Walker

Department of Anatomy, Michigan State University, East Lansing, Michigan 48824, USA

Joan Quarles

Department of Anatomy, Michigan State University, East Lansing, Michigan 48824, USA

The frequency of spontaneous embryonic muscular movements was recorded for embryos from mice treated with cortisone or triamcinolone. Movement was significantly reduced in A/J strain mouse embryos exposed to these anti-inflammatory agents. Cleft palates induced by the drugs may originate from failure of the embryonic tongue to be withdrawn from between the palatine shelves.

Journal of Dental Research, Vol. 54, No. 6, 1200-1206 (1975)
DOI: 10.1177/00220345750540061701
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B. E. Walker
Palate Morphology and Fetal Movements in Mice After DPH
Journal of Dental Research, July 1, 1979; 58(7): 1740 - 1747.
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