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Journal of Dental Research
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Organic Polymeric Polyphosphonates as Potential Preventive Agents of Dental Caries : In Vitro Experiments

M. Anbar

Stanford Research Institute, Menlo Park, California 94025, USA

G.A. St. John

Stanford Research Institute, Menlo Park, California 94025, USA

A.C. Scott

Stanford Research Institute, Menlo Park, California 94025, USA

Organic polymeric polyphosphonates adsorb on enamel surfaces in the form of a monolayer and inhibit calcium and fluoride ion transport but not that of phosphate ions. The polymers investigated include phosphonated polyethylene, polyvinylphosphonate, and polyvinylbenzylphosphonate. The adsorption of proteins on enamel, as exemplified by human serum albumin, is diminished and the adsorbed protein is more readily desorbed from surfaces with polymeric polyphosphonates. These jendings may offer an explanation for the anticariogenic effect of polymeric polyphosphonates.

Journal of Dental Research, Vol. 53, No. 4, 867-878 (1974)
DOI: 10.1177/00220345740530041801
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E. P. Farley, R. L. Jones, and M. Anbar
Improved Adhesion of Acrylic Restorative Materials to Dental Enamel by Precoating with Monomers Containing Phosphonate Groups
Journal of Dental Research, August 1, 1977; 56(8): 943 - 952.
[Abstract] [PDF]

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M. Anbar and E.P. Farley
Potential Use of Organic Polyphosphonates as Adhesives in the Restoration of Teeth
Journal of Dental Research, July 1, 1974; 53(4): 879 - 888.
[PDF]