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Journal of Dental Research
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Studies in the Design and Analysis of Dental Experiments: 14. Replicate Latin Squares

Andre A.O. Varma

School of Public Health of the Faculty of Medicine and the School of Dental and Oral Surgery, Columbia University, New York, New York 10032, USA

Neal W. Chilton

School of Public Health of the Faculty of Medicine and the School of Dental and Oral Surgery, Columbia University, New York, New York 10032, USA

Austin H. Kutscher

School of Public Health of the Faculty of Medicine and the School of Dental and Oral Surgery, Columbia University, New York, New York 10032, USA

Three doses of a lozenge were administered in two locations to 30 individuals (including six smokers) assigned to five 6 by 6 Latin squares. The two locations, the corresponding dose-response curves, and the effect of smoking were compared. No significant differences in the dissolution times were found.

Journal of Dental Research, Vol. 52, No. 1, 23-25 (1973)
DOI: 10.1177/00220345730520012801
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