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Journal of Dental Research
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Patterns of Dental Caries in Osborne-Mendel and NIH Black Rats in Relation to Length of the Caries Test Period

Rachel H. Larson

Disease Prevention and Therapeutics Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20014, USA

Carol S. Zickus

Disease Prevention and Therapeutics Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20014, USA

Both Osborne-Mendel and NIH Black rats developed carious lesions on the smooth surfaces and in the sulci during the first week on an intensive caries-test challenge. The number and size of lesions continued to increase throughout a ten week experiment. Progression on different surfaces varied with the strain, but final levels were not significantly different.

Journal of Dental Research, Vol. 51, No. 5, 1375-1381 (1972)
DOI: 10.1177/00220345720510052101
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