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Journal of Dental Research
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Histochemical Investigation of the Modal Specificity of Taste

Bruce Trefz

School of Dentistry, University of Michigan, Ann Arbor, Michigan 48104, USA

The taste mechanism was investigated in a primate (Macaca mulatta). Based on the hypothesis that intracellular enzymes contribute to the transduction of tastes to electric impulses by taste cells, a histochemical survey of the activity of several enzymes was made on taste buds from regions of the mouth associated with sweet, salt, sour, and bitter tastes. Considerable differences were noted among the modalities, which confirmed the hypothesis. An exclusively bitter enzyme was identified.

Journal of Dental Research, Vol. 51, No. 5, 1203-1211 (1972)
DOI: 10.1177/00220345720510050601
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