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Effect of Undernutrition During the Perinatal Period on Caries Development in the Rat

Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cam-bridge, Massachusetts, USA 02139

L.P. Di Orio

Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cam-bridge, Massachusetts, USA 02139

L. Menaker

Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cam-bridge, Massachusetts, USA 02139

S. Miller

Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cam-bridge, Massachusetts, USA 02139

The manipulation of diets, foster mothers, and progeny has made it possible to study and differentiate the effect of undernutrition during pregnancy and lactation on body growth, incisor and molar weight, and dental caries in rats. Rats undernourished during lactation were retarded in their growth and development and had high caries scores. These effects were not observed when the nutritional stress was imposed during gestation.

Journal of Dental Research, Vol. 49, No. 5, 1091-1098 (1970)
DOI: 10.1177/00220345700490051601


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