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The Interaction of Salivary Proteins with Tooth Surface
Kenneth M. Pruitt
Institute of Dental Research and Laboratory of Molecular Biology, Medical Center, University of Alabama, Birmingham, Alabama 35233
Robert C. Caldwell
Institute of Dental Research and Laboratory of Molecular Biology, Medical Center, University of Alabama, Birmingham, Alabama 35233
Andrew D. Jamieson
Institute of Dental Research and Laboratory of Molecular Biology, Medical Center, University of Alabama, Birmingham, Alabama 35233
Robert E. Taylor
Institute of Dental Research and Laboratory of Molecular Biology, Medical Center, University of Alabama, Birmingham, Alabama 35233
Studies of the adsorption of human salivary proteins, in general, and the enzymes amylase, lysozyme, and neuraminidase, in particular, reveal that these proteins differ in their affinities for the surface of enamel. The enzymes studied retained their enzyme activity in the adsorbed state. Only amylase was desorbed by water; lysozyme was desorbed by its substrate; and all three enzymes, as well as most other adsorbed proteins, were desorbed by phosphate.
Journal of Dental Research, Vol. 48, No. 5,
818-823 (1969)
DOI: 10.1177/00220345690480053501
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