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Journal of Dental Research
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Squamous Carcinoma of the Lip: A Study of the Interface Between Neoplastic Epithelium and the Underlying Mesenchyma

J. Harold Jones

Departments of Pathology and Dental Surgery, The Queen's University, Belfast, Northern Ireland

J.I. Coyle

Departments of Pathology and Dental Surgery, The Queen's University, Belfast, Northern Ireland

In a study of 50 squamous carcinomas of the lower lip, 25 metastasized and 25 were successfully treated by simple resection. Lack of differentiation, a poor lymphocytic response and, in particular, the formation of a loose, alcian blue and Hale positive fibroblastic stroma were unfavorable prognostic signs.

Journal of Dental Research, Vol. 48, No. 5, 702-708 (1969)
DOI: 10.1177/00220345690480051601
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