Click on image to view larger version.


Figure 1


Figure 1. Multipoint parametric dominant and recessive linkage results summary of the two genome-wide scans for low caries susceptibility loci (DMFT categories 1 and 2, assigned as ‘affected’) and high caries susceptibility loci (DMFT categories 3 and 4, assigned as ‘affected’) in 46 families. Bars indicate the most significant LOD score results in each chromosome. In addition to chromosomes 5 and 13 that showed LOD scores above 2.0, several chromosomes (1, 2, 3, 4, 7, 8, 10, 11, 12, 14, 17, 18, and 19) showed LOD scores above 1.0. DMFT = Decayed, Missing due to caries, Filled Teeth; low DOM = multipoint parametric linkage analysis with a dominant model in low caries susceptibility; low REC = multipoint parametric linkage analysis with a recessive model in low caries susceptibility; high DOM = multipoint parametric linkage analysis with a dominant model in high caries susceptibility; high REC = multipoint parametric linkage analysis with a recessive model in high caries susceptibility.