Figure 1. Distribution of total TACE amounts in GCF from healthy persons (n = 21), those with gingivitis (n = 22), chronic periodontitis (n = 28), aggressive periodontitis (n = 25), and immunosuppressed persons with chronic (IS-Chronic) periodontitis (n = 11). The individual values represent the total amounts of TACE (pg/30 sec) in each person. Values significantly different from those in healthy persons (*p < 0.001) and those with gingivitis (⁺p < 0.005).