Figure 2. Supernatant of arrested oral fibroblasts enhanced the proliferation and migration of oral squamous carcinoma cells through MMP-2 activity. (a,b) Growth curves for SAS and OC3, respectively. (c,d) Migration for SAS and OC3, respectively. SAS cells were cultured in media containing 2% and 0.5% fetal bovine serum in (a) and (c), respectively. Values are expressed as means ± SE from 3 individual analyses. *p < 0.05; **p < 0.01; in comparison with controls. #p < 0.05; ##p < 0.01; in comparison with cells without OA-Hy treatment.