Figure 2. 3-D profile of genes showing a statistically significant (P < 0.05) up- or down-regulation of mRNA expression in response to a time-dependent exposure to a uni-axial, intermittent tensile mechanical strain of 12%. Two cell adhesion molecules, 3 BMPs, MSX1, and SOX9 were among the genes whose regulation appears to be sensitive to changes in their mechanical environment. Fold differences are represented on a logarithmic scale. Values on the graph floor in parentheses are displayed for negatively regulated genes and correspond to those represented in the Table.