Figure 1. Conventional and Cumulative Meta-analyses of 5 Trials of Systemic Antimicrobials as an Adjunct to Scaling and Root Planing for All/Moderate Periodontal Pockets: Difference in Mean Gain in Clinical Attachment Level and 95% CI (SRP + antimicrobial vs. SRP alone) in mm. Key to Figs.: Aug, Augmentin^®; Clin, Clindamycin; Dox, Doxycyline; Met, Metronidazole; Met+Amo, Metronidazole and Amoxicillin in combination; Rod, Rodogyl^® (Metronidazole and Spiramycin in combination); Spi, Spiramycin; Tet, Tetracycline; and Tet/Spi, Tetracycline or Spiramycin.