Figure 3. Comparison of IL-1β and PGE₂ production between aggressive periodontitis and non-periodontitis subjects (n = 17, each group). Whole-blood cultures were incubated with 0, 1, 3, and 10 ng/mL of P. gingivalis LPS for 48 hrs and then assessed for IL-1β and PGE₂ production by ELISA. Results are the mean ± SE.