Figure 3. The temporal pattern of Ihh expression (A, n = 10) and the replicating mesenchymal cells’ population (B, BrdU labeling index, n = 5) in condylar cartilage during natural growth and mandibular advancement. Values were mean ± SD. Significant difference between two groups is marked with asterisks (*p < 0.05, **p < 0.01, ***p < 0.001).