Figure 3. Effect of TEGDMA on GSTP1 activity in a cell-free system. (Panel A) Time-course activity of purified GSTP1 after TEGDMA treatment at the concentration of 1 mM. (Panel B) GSTP1 activity following treatment with various concentrations of TEGDMA for 90 min. (Panels C,D) TEGDMA-induced inhibition of GST activity as a function of concentrations of GSH and CDNB, respectively. Inserts in panels C and D show the Lineweaver-Burk representation of the data. The data represent the means (± SD) of triplicate experiments.